Dementia, munjira zake zambiri, imakhala ndi katundu wambiri pa anthu 50 miliyoni omwe akhudzidwa padziko lonse lapansi, komanso awo osamalira.

Gawo lina la kuchepa kwazindikiritso limawonedwa ngati gawo lokalamba. Dementia, kumbali inayo, imapangitsa izi kuchepa "kukhala", pang'onopang'ono kukumbukira zinthu, kuganiza, kulunjika, kuwerengera ndi kuphunzira maluso, kumvetsetsa ndi kuweruza [1].

Vuto losatha sili kupeza njira zatsopano komanso zabwino zamankhwala komanso kupeza zidziwitso zoyenera zomwe zimatilola kulosera zamtundu wazovuta zomwe munthu angakhale nazo pamoyo wawo.

Phunziro la Gustavson ndi anzawo [2] adayesa kuti adziwe luso muzoyesera za ma neuropsychological kuti alosere kufooka kwamtundu wamatumbo (MCI) mwa anthu akuluakulu athanzi. Olembawo amayang'ana kwambiri kukumbukira kwa episodic ndi kupitirira kusinthasintha kwa semantic monga olosera, komanso pamgwirizano pakati pa zinthu ziwiri izi.

Chosangalatsa pakufufuza kwawo chinali kusankha kwa gulu linalake la anthu oti awatchule: mapasa osankhidwa kuchokera kwa abambo omwe adagwira ntchito yankhondo pakati pa 1965 ndi 1975 (wazaka 51 mpaka 59).

Kuyesa kwa Neuropsychological kunagwiritsidwa ntchito kuti kumveketse kukumbukira kwa episodic ndi mawu omveka bwino, komanso kuzindikira, onse poyambira phunziroli komanso patatha zaka zisanu ndi chimodzi. Anthu okhawo omwe ali ndi mulingo wazizolowezi pa kafukufuku woyamba ndiosankhidwa kuti achite nawo phunziroli.

Pamene chidwi chosanthula phunziroli chidawunikidwa, olemba adapeza kuti kupita patsogolo kwa MCI kunanenedweratu ndi cholembera chochepa pamasewera olimbitsa thupi komanso kukumbukira zochitika kumayambiriro kwa phunziroli. Makamaka, kukumbukira kwa episodic kumawoneka ngati kuneneratu kupita patsogolo pa MCI amnesic, ngakhale kusinthasintha kwamasewera kumathandizanso kuti zisachitike.

Kuphatikiza apo, kukumbukira kwapadera, koma kosachita kusimba pang'ono, kumawonekeranso kulosera za MCI zomwe siziri zamisala, motero, kumapereka lingaliro lakuti ikhoza kukhala njira yodzutsa kuitana kuchepa kwamphamvu kwazidziwitso m'malo mongokhala m'malo okhudzana ndi kukumbukira.

Kupeza kwina kosangalatsa ndikuwonetsetsa kuti kusinthasintha kwa malingaliro ndi malingaliro a episodic kumawoneka ngati okhudzana koma izi, malinga ndi olemba, zitha kudzipeza kuchokera ku ma genetic chifukwa zomwe mumayeso awiriwa zimasinthanso chimodzimodzi m'magulu awiriawiri.

Olembawo adatsimikiza kuti kukumbukira kwa episodic ndi kusinthasintha kwa semantic ziyenera kugwiritsidwa ntchito ngati zisonyezo zowopsa za kuchepa kwamtundu wa anthu wamba. Ngakhale kufunikira kwa pentopeni Zachilengedwe zakuzindikira (monga zomwe PET zimapeza) sizingakane

Gustavson ndi ogwira nawo ntchito amakhulupirira kuti njira yabwino ikhoza kuphatikiza chidziwitso kuchokera kwa zolembera zazidziwitso ndi chidziwitso chochokera kuzomwe zimayesedwa komanso kukumbukira kukumbukira kuti anthu azathanzi azitha.

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